Overview
What to know about Basivertebral Nerve Ablation
Some chronic low back pain comes from the vertebral endplates — the thin layers of bone and cartilage on the top and bottom of each vertebra, right next to the discs. When endplates are damaged and inflamed, pain signals travel through the basivertebral nerve, which runs inside the vertebral body. Doctors call this vertebrogenic low back pain. It is typically a deep, aching pain in the middle of the lower back that is worse with sitting or bending forward and does not shoot down the leg[8].
Basivertebral nerve ablation — sometimes known by the brand name Intracept, which is how many patients search for it — uses radiofrequency heat to switch off that nerve from inside the bone. It is meant for a specific group: adults with long-lasting low back pain and MRI findings called Modic type 1 or type 2 changes in one or more vertebrae from L3 to S1[1]. At Pain Physicians NY in Gramercy / Kips Bay, our board-certified physicians review your symptoms, exam and MRI together before recommending it.
How it works
How the procedure works
The basivertebral nerve enters the back of each vertebral body through a small channel and branches out toward the endplates. Using live X-ray, the physician passes a narrow tube through the pedicle — the bony bridge on the back of the vertebra — into the center of the bone. A radiofrequency probe heats the area where the nerve branches, which Medicare’s coverage policy describes as 85°C for 15 minutes, creating a small lesion that stops the nerve from carrying pain signals[1].
Up to four vertebral bodies can be treated in one session, and Medicare covers each vertebra only once in a lifetime[1]. The Intracept system is FDA-cleared through the 510(k) pathway, meaning the FDA found it substantially equivalent to an earlier legally marketed device; clearance is not the same as FDA approval[9].
Candidacy
Who it helps
Often a good fit if you have
- Low back pain for at least 6 months that limits your daily function[1]
- At least 6 months of non-surgical care — such as physical therapy, exercise, medicines or injections — without enough relief[1]
- An MRI showing Modic type 1 or type 2 changes in one or more vertebrae from L3 to S1[1]
- Pain mostly in the center of the lower back, often worse with sitting, standing or bending forward, without leg pain, numbness or weakness as the main problem[8]
- No other likely cause that needs treatment first, such as a fracture, tumor, infection or significant deformity[1]
May not be right if
- Pain that is mainly sciatica or leg symptoms from spinal stenosis — an epidural steroid injection or the MILD procedure may fit better[1]
- Osteoporosis, a compression fracture or spinal cancer at the level to be treated — painful fractures are evaluated for kyphoplasty instead[1]
- Active infection, pregnancy, a bleeding disorder, or severe heart or lung disease[1]
- Prior surgery at the level to be treated (an older discectomy or laminectomy may be acceptable), or imaging that better explains your pain, such as a large disc herniation or a slipped vertebra[1]
Your visit
What to expect
Step 1
Before
Evaluation and MRI review
Your physician reviews your history, examines your back and studies a recent lumbar MRI for Modic changes. Other pain sources — facet joints, sacroiliac joints, discs and nerves — are considered too. Medicare also requires a multidisciplinary evaluation that includes a psychological as well as a physical assessment[1].
Medication review
Tell us about every blood thinner and supplement you take. Because instruments pass into the bone, your physician will make a plan for these medicines using interventional pain guidelines and the advice of the doctor who prescribed them[10]. Never stop a blood thinner on your own.
Day-of planning
Follow the fasting instructions for sedation and arrange for an adult to take you home.
Step 2
During
Sedation and positioning
You lie face down. You receive moderate (twilight) sedation or general anesthesia, and the skin over your lower back is numbed[1].
Access through the pedicle
Guided by live X-ray, the physician passes a narrow access tube through a small skin opening and the pedicle into the vertebral body, then steers a curved instrument toward the center of the bone where the nerve branches.
Radiofrequency ablation
A radiofrequency probe heats the target to create a small lesion[1]. The steps are repeated at each planned level, and the small skin openings are closed and covered.
Step 3
After
Recovery and going home
You rest in the recovery area until the sedation wears off, then go home the same day with your driver.
The first few weeks
Soreness and a temporary flare of back pain are common for several days. Walking is encouraged; avoid heavy lifting until cleared.
Follow-up
Improvement often builds gradually; both randomized trials measured their main results at 3 months[2][4]. Call us for fever, new leg weakness or numbness, or pain shooting down a leg.
Performed at Pain Physicians NY, Gramercy / Kips Bay, East 23rd Street, or at an affiliated ambulatory surgery center.
Types & approaches
Basivertebral Nerve Ablation (Intracept): types and approaches
What are Modic changes?
Modic changes are MRI patterns in the bone marrow next to the endplates. Type 1 changes reflect inflammation and swelling (edema) in the bone; type 2 changes reflect normal marrow being replaced by fat[1]. One of these two types was required to enter both randomized trials of this treatment[2][4]. Your physician also looks for a match between the MRI, where your pain is and your exam.
Basivertebral nerve ablation vs. facet radiofrequency ablation
Both use radiofrequency heat on a nerve, but they treat different pain sources. Facet radiofrequency ablation treats arthritis of the small joints at the back of the spine, needs positive medial branch blocks first, and can be repeated if pain returns. Basivertebral nerve ablation treats endplate pain at the front of the spine, relies on MRI findings rather than a test block, and Medicare covers it once per vertebra[1]. Some people have more than one pain source, so your physician may evaluate both.
Treatment pathway
What often comes next
You are here
Basivertebral Nerve Ablation (Intracept)
Safety
Risks and side effects
- Soreness or bruising where the instruments entered (common)
- Temporary leg pain, tingling or numbness from irritation of a nearby nerve root — in the INTRACEPT trial, 13 of 127 procedures (10.2%) were followed by non-serious leg pain that resolved in a median of 43 days[5]
- Reactions to sedation or anesthesia
- Infection or bleeding (uncommon); rare reports include bleeding deep in the abdomen and temporary weakness or numbness[6]
- No relief, especially if most of your pain comes from discs, facet joints or nerves rather than the endplates; follow-up studies have not reported delayed complications[6]
Evidence
What the research shows
Two randomized trials support this treatment. The SMART trial assigned 225 patients to ablation or a sham (placebo) procedure. At 3 months, disability scores (Oswestry Disability Index, ODI) improved by 20.5 points with ablation versus 15.2 points with sham, and 75.6% versus 55.3% had a meaningful improvement[2] — a reminder that placebo effects in back pain are real.
The INTRACEPT trial compared ablation with continued standard care in 140 patients. At 3 months, ODI improved by 25.3 points with ablation versus 4.4 points with standard care[4]; at 12 months, 64% of treated patients had at least 50% pain relief and 29% were pain-free[5]. Patients knew which treatment they received, so expectations may explain part of the difference.
A 2022 systematic review rated the evidence as moderate quality and estimated that 64% of patients reach at least 50% pain relief at 12 months[6]. An earlier review found that, compared with sham, the share reaching 50% pain relief was not clearly higher, although function improved more[7]. Both trials were funded by the device’s manufacturer, and results beyond the first year come from treated patients without a comparison group[6][3].
Conditions
Conditions this can help
FAQs
Basivertebral Nerve Ablation (Intracept): frequently asked questions
Who is a good candidate for the Intracept procedure?
A good candidate has chronic low back pain from the vertebral endplates. Medicare in New York requires at least 6 months of pain that limits function, at least 6 months of non-surgical care that has not helped enough, and Modic type 1 or 2 changes on MRI in one or more vertebrae from L3 to S1[1]. The pain is usually in the center of the lower back and worse with sitting or bending forward, rather than shooting down the leg[8].
Who is not a candidate for basivertebral nerve ablation?
You are not a good candidate if your main problem is sciatica or leg symptoms from spinal stenosis, or if you have osteoporosis, a compression fracture, spinal cancer or an infection at the level to be treated. Medicare also excludes pregnancy, bleeding disorders, severe heart or lung disease, prior fusion at that level, a body mass index over 40 and active untreated substance use[1]. A large herniated disc or slipped vertebra that explains your pain is usually addressed first.
Are you asleep during the Intracept procedure?
You may be fully asleep or deeply relaxed, depending on the anesthesia plan. Medicare’s policy describes the procedure as performed with moderate (conscious) sedation or general anesthesia[1]. With moderate sedation you are drowsy and may remember little afterward, and the skin is numbed. Most people feel pressure rather than sharp pain, and the procedure usually takes about an hour.
How should I prepare for basivertebral nerve ablation?
Bring your MRI, a list of all medicines and supplements, and your insurance information to your consultation. Your physician will review any blood thinners using interventional pain guidelines and coordinate with the doctor who prescribed them — never stop one on your own[10]. On the day itself, follow the fasting instructions and bring an adult who can drive you home.
How effective is the Intracept procedure?
In well-selected patients, most people report meaningful improvement. In the INTRACEPT trial, 64% of treated patients had at least 50% less pain at 12 months and 29% were pain-free[5]. A 2022 review rated the evidence as moderate quality[6]. Results vary: in the sham-controlled SMART trial, the placebo group also improved substantially, and the gap between groups at 3 months was modest[2].
How long does relief from basivertebral nerve ablation last?
For people who respond, relief has lasted for years in follow-up studies. In the SMART trial’s long-term report, 100 of 117 treated patients were reviewed at an average of 6.4 years; 66% reported more than 50% pain reduction and 34% reported complete relief[3]. These long-term results did not include a comparison group, so they are encouraging but less certain than the 3-month randomized results.
What is recovery like after basivertebral nerve ablation?
Most people go home the same day and return to light activities within a few days. Soreness at the needle sites and a temporary increase in back pain are common at first. Some people develop temporary leg pain from nerve-root irritation; in the INTRACEPT trial this resolved in a median of 43 days[5]. Your physician will advise when to resume exercise and lifting.
What are the downsides of Intracept?
The main downsides are that it helps only one specific type of back pain, and some people do not improve. Temporary leg pain is the most commonly reported side effect, usually from irritation of a nerve near the pedicle[6]. Infection and serious bleeding are rare. The research supporting it was funded by the device’s manufacturer[6], and Medicare covers each vertebra only once in a lifetime[1].
Is the Intracept procedure covered by insurance?
Medicare in New York covers it for patients who meet specific criteria. National Government Services — Medicare’s contractor for New York, renamed Wellpoint Federal in 2026 — has a coverage policy (LCD L40302) in effect for services from July 15, 2026[1]. Commercial plans vary: some still consider the procedure investigational, which is a common reason for denials, and most require prior authorization. Workers’ compensation and no-fault claims follow their own approval rules. Our staff verifies your benefits before scheduling.
Can basivertebral nerve ablation be repeated?
Each vertebra is generally treated only once. Medicare in New York covers ablation once per vertebral body from L3 to S1 per lifetime, with up to four vertebral bodies treated in one procedure[1]. If pain later develops at a different level that meets the criteria, that level may be considered. If pain persists after a technically successful treatment, your physician will look for other sources rather than repeating the same level.
What are the alternatives if I am not a candidate?
Alternatives depend on where your pain comes from. Active physical therapy and a home exercise program remain the foundation for most chronic low back pain. If the facet joints are suspected, medial branch blocks and radiofrequency ablation may help; for leg pain from a pinched nerve, an epidural steroid injection is often considered. For persistent pain after other treatments, spinal cord stimulation or a surgical opinion may be options.
Where is basivertebral nerve ablation performed?
It is performed in our office or at an affiliated ambulatory surgery center, depending on your anesthesia needs and insurance. Consultations take place at our practice on East 23rd Street in Gramercy / Kips Bay, Manhattan. You go home the same day, but you will need an adult to accompany you because of the sedation. Contact us to schedule an evaluation.
Related
Related treatments
Spinal RFA
A heat-based treatment that quiets the small nerves carrying arthritis pain from your spine’s facet joints, after test blocks confirm the source.
Medial Branch Block
A quick, targeted test that shows whether your facet joints are causing your back or neck pain.
Epidural Steroid Injections
An X-ray-guided injection that calms an irritated spinal nerve to ease sciatica, arm pain and pain from spinal stenosis.
Discogram
A carefully selected diagnostic test that shows whether a specific disc is the source of chronic back or neck pain — used today mainly to guide surgical decisions.
Spinal Cord Stimulation
A small implanted device that sends mild electrical pulses to the spinal cord to quiet chronic nerve pain — always tested first with a short trial.
Sources
Last updated November 3, 2026. This page is educational and does not replace a consultation with your physician.
- 1.LCD L40302: Thermal Destruction of the Intraosseous Basivertebral Nerve (BVN) for Vertebrogenic Lower Back Pain — Centers for Medicare & Medicaid Services / Wellpoint Federal (formerly National Government Services), 2026 · Regulatory
- 2.Intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: a prospective randomized double-blind sham-controlled multi-center study — European Spine Journal (Fischgrund JS et al.), 2018 · Clinical trial
- 3.Long-term outcomes following intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: 5-year treatment arm results from a prospective randomized double-blind sham-controlled multi-center study — European Spine Journal (Fischgrund JS et al.), 2020 · Clinical trial
- 4.A prospective, randomized, multicenter study of intraosseous basivertebral nerve ablation for the treatment of chronic low back pain — The Spine Journal (Khalil JG et al., INTRACEPT Trial Investigators), 2019 · Clinical trial
- 5.Prospective, randomized, multicenter study of intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: 12-month results — Regional Anesthesia & Pain Medicine (Smuck M et al.), 2021 · Clinical trial
- 6.The Effectiveness of Intraosseous Basivertebral Nerve Radiofrequency Ablation for the Treatment of Vertebrogenic Low Back Pain: An Updated Systematic Review with Single-Arm Meta-analysis — Pain Medicine (Conger A et al.), 2022 · Review
- 7.The Effectiveness of Intraosseous Basivertebral Nerve Radiofrequency Neurotomy for the Treatment of Chronic Low Back Pain in Patients with Modic Changes: A Systematic Review — Pain Medicine (Conger A et al.), 2021 · Review
- 8.Basivertebral Nerve Ablation — StatPearls, NCBI Bookshelf, 2026 · Medical reference
- 9.510(k) Premarket Notification K222281: Intracept Intraosseous Nerve Ablation System — U.S. Food and Drug Administration, 2022 · Regulatory
- 10.Interventional spine and pain procedures in patients on antiplatelet and anticoagulant medications (second edition) — Regional Anesthesia & Pain Medicine (Narouze S et al.), 2018 · Guideline
