Spinal Injections

Epidural Blocks

An X-ray-guided injection that calms an irritated spinal nerve to ease sciatica, arm pain and pain from spinal stenosis.

Also called: Epidural steroid injection · ESI · Epidural injection for back pain · Lumbar epidural steroid injection · Transforaminal epidural steroid injection · Interlaminar epidural steroid injection · Cervical epidural steroid injection · Caudal epidural injection

Procedure time
15–30 minutes
Anesthesia
Local anesthetic; light sedation only if needed
Guidance
Fluoroscopy (live X-ray) with contrast dye
Setting
Outpatient — home the same day
Downtime
Most people resume usual activities the next day
Lumbar spine (side view): Image-guided needle placement, Medication reaches the nerve root opening, Inflammation and pain signals settleLower back · side view
  1. Image-guided needle placement
  2. Medication reaches the nerve root opening
  3. Inflammation and pain signals settle

Simplified illustration, not to scale.

85%
Success Rate
6mo+
Pain Relief Duration
<24hr
Recovery Time

Overview

What to know about Epidural Blocks

An epidural steroid injection (ESI), also called an epidural block, places anti-inflammatory steroid medicine — usually with a numbing medicine — into the epidural space, the fat-filled space inside the spinal canal that surrounds the spinal nerves. It is used mainly for radicular pain: pain that travels from the lower back into the buttock and leg (sciatica), or from the neck into the arm, most often because a herniated disc or spinal stenosis is irritating a nerve root[1].

An epidural injection does not repair a disc or widen a narrowed canal, and its effect is usually temporary. The goal is to calm the nerve enough that you can move more comfortably, keep up with physical therapy and give the problem time to settle[1]. Our board-certified physicians perform epidural injections in our office in Gramercy / Kips Bay on East 23rd Street, or at an affiliated ambulatory surgery center.

How it works

How the procedure works

When a disc herniates, or arthritis narrows the openings where nerves leave the spine, the nearby nerve root can become inflamed. The steroid reduces that inflammation, and the local anesthetic gives short-term numbing. Medicine can reach the epidural space from the side next to a single nerve (transforaminal), from directly behind between two vertebrae (interlaminar) or through a small opening near the tailbone (caudal)[1]. Live X-ray and contrast dye confirm that the medicine flows into the epidural space and not into a blood vessel; Medicare requires CT or fluoroscopic guidance with contrast[3].

The FDA has not approved corticosteroids for epidural injection, and their safety and effectiveness for this use have not been formally established. Since 2014 the FDA has required a label warning about rare but serious neurologic events after epidural injection, including spinal cord injury, paralysis, stroke, vision loss and death[4][5]. Safety recommendations developed with the FDA’s Safe Use Initiative — including image guidance and a non-particulate steroid for certain approaches — aim to make these events even less likely[6].

Candidacy

Who it helps

Often a good fit if you have

  • Pain that radiates from the lower back into the buttock or leg (sciatica), or from the neck into the arm[1]
  • A herniated disc or spinal stenosis that matches your symptoms on MRI or CT[3]
  • Pain lasting at least four weeks despite physical therapy, medicines or activity changes[3]
  • Leg pain or heaviness with walking or standing from lumbar spinal stenosis[3]

May not be right if

  • Back or neck pain that stays in the spine without spreading into a limb — testing the facet joints or SI joint is usually more useful[13]
  • An active infection, a fever, a bleeding disorder, or pregnancy or possible pregnancy[13]
  • Poorly controlled diabetes or high blood pressure, which may need attention first[13]
  • New bowel or bladder problems, rapidly worsening weakness, or suspected infection, fracture or cancer — these need urgent evaluation, not an injection[1]

Your visit

What to expect

Step 1

Before

  1. Evaluation

    Your physician reviews your symptoms, exam and MRI or CT to confirm an irritated nerve root and to choose the level and approach.

  2. Medication review

    Tell us about blood thinners, diabetes medicines and any contrast allergy. Epidural injections are intermediate bleeding-risk procedures, so some blood thinners may need to be paused[12] — never stop one without the doctor who prescribed it.

  3. Ride home

    Arrange for someone to take you home, especially if you will receive sedation.

Step 2

During

  1. Positioning and numbing

    You lie on your stomach (for the neck, sometimes on your side), and the skin is cleaned and numbed.

  2. X-ray and contrast

    Your physician guides a thin needle with live X-ray and injects a little contrast dye to confirm it spreads in the epidural space and not into a blood vessel[1].

  3. Medicine

    The steroid, often with a local anesthetic, is injected slowly. You may feel pressure or a brief echo of your usual pain.

Step 3

After

  1. Short observation

    You rest briefly while we check how you feel, then go home the same day.

  2. The first few days

    Numbness wears off within hours. Soreness or a short pain flare is common before the steroid starts to help.

  3. Follow-up

    We check how much and how long the injection helped. Keep up exercise or physical therapy — injections by themselves are not likely to provide long-term relief[13].

Performed at Pain Physicians NY, Gramercy / Kips Bay, East 23rd Street, or at an affiliated ambulatory surgery center.

Types & approaches

Epidural Steroid Injections: types and approaches

Lumbar transforaminal epidural steroid injection

A transforaminal epidural steroid injection (TFESI) reaches the epidural space from the side, through the opening where a single nerve root leaves the spine. This places medicine close to the inflamed nerve and the front of the epidural space, where most disc herniations press, so it is often chosen for one-sided sciatica[1]. Medicare in New York covers up to two transforaminal levels per spinal region in a session[3].

Because small arteries can run near this opening, your physician checks the contrast pattern under live X-ray before injecting. Safety recommendations favor a non-particulate steroid, such as dexamethasone, for most first-time lumbar transforaminal injections[6].

Lumbar interlaminar and caudal epidural injections

An interlaminar injection enters the epidural space from directly behind, between two vertebrae; a caudal injection enters near the tailbone. Both spread medicine more widely, which can help when symptoms affect both legs or several levels, or after spine surgery[1]. Medicare covers one level per session for these approaches[3].

Interlaminar injections are often used for lumbar spinal stenosis, but the evidence there is modest: a large 2014 trial found that adding steroid to a numbing medicine gave minimal or no extra benefit at six weeks[9], and a 2025 review found that epidural steroids possibly reduce disability from stenosis but not short-term pain[8].

Cervical and thoracic epidural steroid injections

Cervical epidural injections treat arm pain, tingling or numbness from a pinched nerve in the neck, usually after six to eight weeks of conservative care; one clinical review reports that about half of patients get a 50% reduction in pain lasting three months[2].

The interlaminar approach is used most often, low in the neck where the epidural space is widest. Cervical transforaminal injections carry higher risks, including rare paralysis or death[2]; safety recommendations say particulate steroids should not be used for them[6], and New York workers’ compensation guidelines do not recommend them[14]. Thoracic (mid-back) injections are less common and may help pain that wraps around the chest from a thoracic disc problem or acute shingles[3].

Pressure-sensing epidural guidance (CompuFlo)

Some physicians use a computer-controlled, pressure-sensing system — sometimes known by the brand name CompuFlo — during interlaminar injections. It continuously measures pressure at the needle tip and shows the drop that occurs when the tip passes through the thick ligament behind the spinal canal into the epidural space.

The CompuFlo Epidural system is FDA-cleared through the 510(k) pathway for real-time verification of needle placement in the lumbar or thoracic epidural space, including the junction of the neck and upper back, in adults[10]. In a randomized trial of 240 patients having lumbar epidural steroid injections, pressure sensing identified the epidural space as reliably as fluoroscopy, with both methods successful in every case[11].

It is an added aid, not a replacement for X-ray: Medicare still requires CT or fluoroscopic guidance with contrast[3]. Research on the system is limited, and it has not been shown to prevent rare serious complications.

Treatment pathway

What often comes next

Safety

Risks and side effects

  • Soreness at the injection site or a temporary flare of pain (common)[7]
  • Temporary numbness or weakness in a leg or arm from the numbing medicine
  • Light-headedness or fainting (a vasovagal reaction)[13]
  • A short-lived rise in blood sugar from the steroid, especially in people with diabetes[13]
  • Headache from an accidental puncture of the fluid sac around the nerves (post-dural puncture headache)[7]
  • Infection, bleeding in the spinal canal (epidural hematoma) or nerve injury (rare)[13]
  • Very rare but serious neurologic events — spinal cord injury, paralysis, stroke, vision loss or death — reported after epidural steroid injection, with and without X-ray guidance[5]

Evidence

What the research shows

A 2020 Cochrane review of 25 placebo-controlled trials found that epidural steroid injections probably reduce leg pain and disability slightly in the short term (up to three months) for people with sciatica, although the average effect was small[7].

A 2025 American Academy of Neurology systematic review of 90 randomized trials concluded that epidural steroids probably reduce short-term pain and disability from cervical and lumbar radiculopathy and possibly reduce longer-term disability, but that evidence is insufficient to show lasting pain relief. For lumbar spinal stenosis, they possibly reduce disability but not short-term pain[8].

In practice, an epidural injection works best as one part of a plan — a window of relief that helps you recover and stay active — rather than as a stand-alone or indefinitely repeated treatment[1].

Conditions

Conditions this can help

FAQs

Epidural Steroid Injections: frequently asked questions

Who is a good candidate for an epidural steroid injection?

The best candidates have pain that travels from the back into a leg, or from the neck into an arm, caused by a herniated disc or narrowing around a nerve that matches their MRI or CT, and that has not improved after several weeks of physical therapy and medicines[1][3]. Epidural injections are not recommended for back or neck pain that stays in the spine without spreading into a limb[13].

How do epidural steroid injections work?

An epidural steroid injection works by reducing inflammation around an irritated spinal nerve. A corticosteroid, usually mixed with a numbing medicine, is placed next to the nerve under live X-ray[1]. The numbing effect wears off within hours, while the steroid aims to calm the nerve over the following days. It does not repair the disc, but it can ease pain enough for you to stay active while healing continues.

How should I prepare for an epidural injection?

Tell us about every medicine you take, especially blood thinners. Epidural injections are intermediate bleeding-risk procedures, so some blood thinners may need to be paused[12] — never stop one on your own; we coordinate with the prescribing doctor. Tell us if you have diabetes, since the steroid can briefly raise blood sugar[13], or if you might be pregnant, and arrange a ride home.

Does an epidural steroid injection hurt?

Most people feel a brief sting from the numbing shot, then pressure rather than sharp pain. A transforaminal injection can briefly reproduce your familiar leg or arm pain. The procedure takes 15 to 30 minutes, and most patients need no sedation; Medicare’s policy notes that moderate or deep sedation is usually unnecessary[3]. Soreness at the injection site for a day or two is common.

How long does an epidural steroid injection last?

Relief varies widely. Some people feel better within a few days and stay better for a long time; others get little benefit. Research shows the clearest benefit in the first three months: a 2025 American Academy of Neurology review found that epidural steroids probably reduce short-term pain and disability from radiculopathy, with insufficient evidence for lasting pain relief[8]. A repeat may be considered if one injection helped a lot.

Can steroid injections cause dizziness or other side effects?

Yes. Some people feel light-headed or faint during or soon after the injection — usually a brief vasovagal reaction that passes with rest[7][13]. Headache and a temporary pain flare can occur[7], and the steroid can briefly raise blood sugar[13]. Some people notice facial flushing or poor sleep for a night or two. Call us for a severe headache when standing, fever or new weakness.

What is the downside of an epidural steroid injection?

Relief is often temporary and may not come at all, and there is a small risk of complications. The FDA has not approved corticosteroids for epidural use and requires a label warning about rare but serious neurologic events, including paralysis, stroke, vision loss and death[4][5]. Careful technique — live X-ray, contrast dye and the right choice of steroid — is designed to reduce that risk[6].

How many epidural injections can I have in a year?

Only a few per year in each region of the spine, and only if the last one clearly helped. Medicare’s policy for New York allows up to four sessions per spinal region in a rolling 12 months, with repeats only after at least 50% improvement lasting three months or more[3]. New York workers’ compensation guidelines allow up to three per region per year[13].

What is the next step if an epidural injection doesn’t work?

Your physician will first recheck the diagnosis — the pain may be coming from the facet joints, the SI joint or elsewhere. Physical therapy remains important. For a disc still pressing on a nerve, endoscopic discectomy or a surgical opinion may be discussed; for spinal stenosis, the MILD procedure; and for long-standing nerve pain, spinal cord stimulation.

Does insurance cover epidural steroid injections?

Medicare and most commercial plans cover them when criteria are met. Medicare’s policy for New York requires nerve-root pain or stenosis symptoms supported by imaging, at least four weeks of conservative care, and image guidance with contrast; it does not cover injections for back or neck pain alone[3]. Commercial plans often require prior authorization. Workers’ compensation follows New York’s Medical Treatment Guidelines[13], and no-fault has its own rules.

What is recovery like, and can I drive afterward?

Recovery is usually quick: you rest briefly, go home the same day and return to normal activities, including work, the next day. Plan not to drive yourself home — the numbing medicine can make a leg or arm feel weak, and you must not drive after sedation. Use ice for soreness, keep a simple pain log and continue your exercises; the injection is meant to help you stay active.

Related

Sources

Last updated November 3, 2026. This page is educational and does not replace a consultation with your physician.

  1. 1.Lumbar Epidural Steroid Injection — StatPearls, NCBI Bookshelf, 2026 · Medical reference
  2. 2.Cervical Epidural Injection — StatPearls, NCBI Bookshelf, 2025 · Medical reference
  3. 3.LCD L39036: Epidural Steroid Injections for Pain Management — Centers for Medicare & Medicaid Services / Wellpoint Federal (formerly National Government Services) · Regulatory
  4. 4.FDA Drug Safety Communication: FDA requires label changes to warn of rare but serious neurologic problems after epidural corticosteroid injections for pain — U.S. Food and Drug Administration, 2014 · Regulatory
  5. 5.Kenalog-40 (triamcinolone acetonide injectable suspension) prescribing information — Warnings: Serious Neurologic Adverse Reactions with Epidural Administration — U.S. Food and Drug Administration (Drugs@FDA), 2014 · Regulatory
  6. 6.Safeguards to prevent neurologic complications after epidural steroid injections: consensus opinions from a multidisciplinary working group and national organizations — Anesthesiology (Rathmell JP et al.), 2015 · Guideline
  7. 7.Epidural corticosteroid injections for lumbosacral radicular pain — Cochrane Database of Systematic Reviews (Oliveira CB et al.), 2020 · Review
  8. 8.Epidural Steroids for Cervical and Lumbar Radicular Pain and Spinal Stenosis Systematic Review Summary — Neurology — American Academy of Neurology Guidelines Subcommittee, 2025 · Review
  9. 9.A randomized trial of epidural glucocorticoid injections for spinal stenosis — New England Journal of Medicine (Friedly JL et al.), 2014 · Clinical trial
  10. 10.510(k) Premarket Notification K221702: CompuFlo Epidural Computer Controlled Anesthesia System — U.S. Food and Drug Administration, 2023 · Regulatory
  11. 11.Objective epidural space identification using continuous real-time pressure sensing technology: a randomized controlled comparison with fluoroscopy and traditional loss of resistance — Anesthesia & Analgesia (Gebhard RE et al.), 2019 · Clinical trial
  12. 12.Interventional spine and pain procedures in patients on antiplatelet and anticoagulant medications (second edition) — Regional Anesthesia & Pain Medicine (Narouze S et al.), 2018 · Guideline
  13. 13.Mid and Low Back Injury Medical Treatment Guidelines — New York State Workers’ Compensation Board, 2022 · Regulatory
  14. 14.Neck Injury Medical Treatment Guidelines — New York State Workers’ Compensation Board, 2022 · Regulatory

Talk to a specialist about Epidural Steroid Injections

Our board-certified physicians will review your history and imaging and explain every option, from the least invasive up.